The RAC Rescue helicopter has taken a man to Royal Perth Hospital following a crash on Northam-York Road, near the intersection of Buckingham Road, in York.
The incident, involving the single vehicle and a tree was reported to emergency services around 11.40am on Thursday.
Volunteer Fire and Rescue Service firefighters helped remove the man from the vehicle.
It is understood the man has serious injuries.
The RAC Rescue helicopter was expected to land at the hospital around 2.45pm.